When purchasing on a subscription plan you can save 15%. The subscription can be paused or canceled at any time. Ongoing orders are $41.95 when on a subscription plan. We also offer single pack orders at $49.95.

PreCardix® is a safe and effective supplement for cardiovascular health. PreCardix® contains unique bioactive marine peptides that have been studied in peer-reviewed clinical trials for its effect on blood pressure health. The clinical documentation was prepared by a third party clinical research organization (CRO) in accordance with clinical research standards governed by ethics review committees and process in Europe and North America.

PreCardix® is the result of over a decade of research and multi-million dollar investment conducted in partnership between the University of Tromso Norway and the R&D Institute Norfima and Marealis Health Inc. PreCardix®’s unique refined shrimp peptide concentrate (Marealis RSPC) is derived from the proteins of fresh, cold water Arctic shrimps (Pandalus Borealis) through a controlled enzymatic hydrolysis process. Enzymatic hydrolysis breaks down larger protein chains into smaller, peptide chains. These peptide chains are further refined into Marealis RSPC through a proprietary process resulting in a clinically proven bioactive peptide with an ACE inhibiting action.

Our current pricing supports on-going quality and future R&D.

PreCardix® is a safe and effective supplement cardiovascular health. Please check with your insurance provider to see if this is something they offer.

Your order will be processed and prepped within 1-2 business days by Amazon FBA. DDelivery time varies by destination. Once your order is shipped out, transit time within Ontario is normally between 2-5 days, depending on your location. Shipping outside Ontario may take approximately 3-7 days, depending on location.

Subscriptions are sent automatically each month.

Once your order is shipped, you will receive an email with tracking information. If for some reason you don’t receive it, please contact us at support@precardix.ca and our customer support team will be happy to provide you with that information and help answer any other questions you might have.

You can safely pay for your Single Order or Subscription through our safe payment processing platforms. If purchasing a Subscription, your credit card will be billed monthly. Your (monthly) order will be shipped 1-2 working days after the billing date. If, for any reason you would like to cancel your subscription, please contact us at support@precardix.ca one week before your billing date or manage your subscription from My account. Your billing date will be clearly noted on your order confirmation form. Please save this information for future reference. If you cancel your order after your billing date, please allow up to one week for a refund to appear on your credit card.

No, you don’t need an account to make a purchase on our website. You can check out as a “Guest” by selecting that option at checkout. However, we recommend creating an account even for a single order. This ensures that all of your information is securely stored and easily accessible for future orders. If you purchase a subscription to PreCardix®, an account will be created for you automatically. To access your account, visit this link: https://precardix.ca/my-account/.

You are able to reset your password on our website precardix.ca. Go to ‘my account’, and then under the ‘login’ section you can click on ‘forgot my password’, follow the steps and you should then receive an email to the account listed on your profile where you can reset your password. If you need any assistance, please contact us at support@precardix.ca.

PreCardix® is available online at precardix.ca, Amazon.ca, Amazon.com, and well.ca, through Naturopathic Doctors across Canada via Fullscript, in-store at Rexall®, Pure Pharmacy, and Pharmasave; and online + in-store at London Drugs, Nature’s Source, and Healthy Planet.

PreCardix® does not require a prescription.

PreCardix® is a safe and effective supplement for cardiovascular health.

PreCardix® is not appropriate for or during:

• Pregnancy or while breast-feeding
• Children under 18 years old
• Individuals with a shellfish allergy
• Patients who have a history of angioedema related to the use of ACEI medication
• Patients with renal artery stenosis

Patients who are on medications or who have pre-existing health conditions should always consult with their health care provider before initiating PreCardix®. Never stop or change your medication without consulting with your health care provider. PreCardix® is not a substitute for medication.

PreCardix® does not have any known serious side effects. It has not been found to cause side effects sometimes associated with ACE inhibitor medication such as dry cough, itching, edema (swelling), high potassium levels, or hypotension (low blood pressure).

PreCardix® may cause moderate nausea and/or stomach discomfort. One case of mild euphoric mood, fatigue, upper abdominal pain, and headache occurred during the clinical trial.

Clinical research has not found any cases of hypotension when taking PreCardix®. There are also no documented cases of hypotension from our customers currently using PreCardix® either.

It’s important to consider various factors that may influence blood pressure readings, including time of day when you measure your blood pressure as blood pressure can fluctuate during the day. Factors that can affect blood pressure include caffeine and alcohol intake, smoking, exercise and stress levels.

To ensure accurate blood pressure readings, avoid smoking, caffeine, alcohol, and exercise 30 minutes before measurement. If feeling anxious or in pain, wait until those feelings have passed. Empty your bladder and sit comfortably in a supported chair with feet firmly planted on the ground.

Keep in mind that blood pressure is an average, and a single high reading is less significant than the overall average.

For the most accurate results, it is recommended to take two separate readings one minute apart, in the morning and evening. PreCardix® has been designed to be taken consistently for at least 8 weeks to achieve optimal results, and it should be continued to maintain those results.

PreCardix® has not been found to increase potassium levels. In the clinical trial, serum potassium levels were measured at baseline and at 8 weeks in all study participants. There was no clinically significant difference between potassium levels at both baseline and at 8 weeks between the placebo and treatment group. However, considering PreCardix® bioactive marine peptides’ ACE-inhibiting action, caution should be taken when using PreCardix® with agents that increase serum potassium such as potassium-sparing diuretics, potassium supplements, and potassium-containing salts. Individuals using any of these combinations should have serum potassium levels monitored frequently.

Share the PreCardix® product monograph with your health care provider who can advise you on drug interactions, contra-indications and other factors related to your health to help determine if PreCardix® is appropriate for you.

PreCardix® should not be used in patients with known shellfish allergies. The active ACE-inhibiting peptides in PreCardix® are derived from the shells of arctic cold-water shrimp.

PreCardix® has not been studied in pregnancy or breastfeeding and should be avoided throughout the entire gestational period due to the potential teratogen effects of ACE inhibitors. Women who are breastfeeding should not take PreCardix®.

Children under the age of 18 should not take PreCardix®.

Any suspected side effects associated with the use of PreCardix® should be reported to Health Canada. For more information regarding reporting online, by mail or fax, visit their Adverse Reaction Reporting website here, or call toll-free at 1-866-234-2345.

PreCardix® bioactive marine peptides have a clinically documented ACE inhibiting action. ACE inhibitors affect blood pressure by preventing ACE (angiotensin-converting enzyme) from converting angiotensin 1 to angiotensin 2. Angiotensin 2 increases blood pressure in several ways, including stimulating sodium and fluid retention and constricting blood vessels. Inhibiting excess levels of ACE reduces angiotensin 2.

PreCardix® bioactive marine peptides have a clinically documented ACE inhibiting action. ACE inhibitors affect blood pressure by preventing ACE (angiotensin-converting enzyme) from converting angiotensin 1 to angiotensin 2. Angiotensin 2 increases blood pressure in several ways, including stimulating sodium and fluid retention and constricting blood vessels. Inhibiting excess levels of ACE reduces angiotensin 2.

PreCardix® bioactive marine peptides have a clinically documented ACE inhibiting action. ACE inhibitors affect blood pressure by preventing ACE (angiotensin-converting enzyme) from converting angiotensin 1 to angiotensin 2. Clinical trials have shown that 89% of participants experienced a significant effect on their blood pressure health within 8 weeks or less. Therefore, we always advise people to try PreCardix® for at least 8 weeks before being able to determine if it works for you.

Take 2 tablets together daily before noon and away from other food, medications, or supplements. Allow 8 weeks to see results. Continue to take daily to maintain results.

PreCardix® is a unique composition of thousands of bioactive marine peptides derived from the shells of arctic cold-water shrimp. These short-chain peptides are isolated through a proprietary hydrolysis process. It is hypothesized by the PreCardix® research and development team that this unique combination of peptides mitigates the adverse effects seen with single-molecule ACE-inhibitors. It should be noted that this is a theory and further research on peptide-specific mechanisms of action is being conducted.

Unfortunately not. The bioactive marine peptides in PreCardix® are extracted through an extensive and patented production process where the natural proteins in the shrimp shells are broken down into smaller amino acid chains (peptides) through a controlled enzymatic hydrolysis process.

The enzymes added in the production process, splice the proteins into smaller fractions and thus create the extraordinary blood pressure health attributes. By consuming shrimps (or shrimp shells) in their natural form, you would be consuming the full length proteins. The body is not able to process the larger proteins into the smaller peptides found in the final PreCardix® tablet.

Therefore, these proteins won’t have the same effect on blood pressure health.

PreCardix® bioactive marine peptides are derived from sustainable cold water Arctic Shrimps (Pandalus Borealis) through a process called controlled enzymatic hydrolysis. This process breaks down shrimp proteins into smaller fragments called peptides. These proprietary PreCardix® peptides have been clinically proven to have a statistically significant effect on blood pressure health.

These peptides remain intact in the digestive system and enter the blood stream where they have an ACE inhibiting action. Further breakdown of these peptides occurs in the blood plasma, liver, and kidneys, and enzymatically where the peptides become amino acids, after the peptides have had the intended effect.

Consult with your primary health care provider before adding PreCardix® along-side other medications or supplements. Do not discontinue current medication without consulting with your health care provider. PreCardix® is not a substitute for medication. Monitor blood pressure regularly.

PreCardix® was not studied in combination with other medications or supplements. Interactions are inferred based on documented interactions of common ACE inhibiting drugs. Other interactions may also occur.

• The effect of PreCardix® on blood pressure may be augmented by other blood pressure medication or natural health products and cause low blood pressure. This effect has been well-documented with individuals combining alpha-blocking medication and ACE inhibitors after the first dose. Monitor for this potential effect.
• PreCardix® bioactive marine peptides did not increase potassium levels in the clinical trial. However, due to the ACE inhibiting action, potassium levels should be monitored frequently, particularly with agents that increase serum potassium, such as potassium-sparing diuretics, potassium supplements, and potassium-containing salts.
• A possible causal relationship between ACE inhibitor treatments and allopurinol (a pharmaceutical treatment for gout) may lead to hypersensitivity. PreCardix® should be used cautiously with allopurinol until further research establishes safety.
• The use of NSAIDs (such as Ibuprofen) may reduce the effect of ACE inhibiting medication. Monitor blood pressure regularly if you are taking NSAIDs with PreCardix®.
• Intravenous iron infusion should be administered cautiously in individuals using PreCardix®. ACE inhibitors may augment the systemic effects of IV iron. Oral iron supplementation is not a concern.
• Individuals taking lithium should have lithium levels monitored frequently. ACE inhibitors may decrease renal elimination of lithium, leading to lithium toxicity (CNS symptoms, ECG changes, renal failure). PreCardix® was not studied along-side lithium medication

Share the PreCardix® product monograph with your health care provider who can advise you on drug interactions, contra-indications and other factors related to your health to help determine if PreCardix® is appropriate for you.

PreCardix® clinical trials were conducted on a healthy population who were not on any type of medication and had no other health conditions other than mild-moderately elevated blood pressure. Individuals with pre-existing medical conditions should speak with their health care provider before introducing PreCardix® to ensure safety and wellbeing. Similarly, individuals who are on any medications or supplements should be closely monitored by their primary health care provider before introducing PreCardix®.

Share the PreCardix® product monograph with your health care provider who can advise you on drug interactions, contra-indications and other factors related to your health to help determine if PreCardix® is appropriate for you.

PreCardix® has not been studied in individuals with a history of angioedema related to the previous use of ACE inhibitors and should be avoided in this population. PreCardix® has not been studied in individuals who have renal artery stenosis and should be avoided in this population based on the known contraindication with pharmaceutical ACE inhibitor medication. Individuals who have an allergy to shellfish should not take PreCardix®.

For additional information please refer to Product Information and Directions.

Always consult with your health care provider before making changes to your blood pressure management plan. PreCardix® does not treat, cure or prevent medical conditions.  Measure and monitor blood pressure regularly. Know the signs of heart attack and stroke. Do not take PreCardix® if you are pregnant, breastfeeding, have renal artery stenosis, history of angioneurotic edema or shellfish allergy.

In our trials and testing, we have conducted extensive research on the safety and efficacy of PreCardix®. While our findings from a toxicology study indicate that doses up to 100 times the recommended daily dose did not cause hypotension, other overdose reactions or safety issues, the dose used in clinical trials was 2 tablets together daily, therefore making this the recommended daily dose.

It is best to take PreCardix® away from food, medications, supplements as well as caffeinated drinks, as these may interfere with the absorption of the product and reduce its positive impact on blood pressure health. Since caffeine can be a factor in elevated blood pressure, it is recommended to measure your blood pressure before and after consuming caffeine to determine potential effects on blood pressure levels. For long-term monitoring, blood pressure should be measured before drinking caffeinated drinks. For additional questions, please contact us at support@precardix.ca.

Follow the directions on the package. The recommended dosage is to take two (2) tablets  (1200mg) together once daily, preferably away from food. Continue to take daily to maintain results. Blood pressure may rise to pre-treatment levels if it is discontinued.

In clinical trials, participants took two tablets of PreCardix® together, in between meals and in the morning.

89% of participants experienced a significant effect on their blood pressure within 8 weeks. This is the reason we advise taking two tablets of PreCardix® (1200mg) together once daily, preferably away from food. Allow 8 weeks (2 packs) to achieve results. Continue to take daily to maintain results.

The reason that we advise to take PreCardix® before noon is the simple fact that in our clinical trial, two tablets of PreCardix® were taken every morning. We recommend taking PreCardix® daily before noon, a few hours before or after medications, and preferably away from natural health products or food to maximize absorption of the bioactive marine peptides. This was the dosing strategy used in the clinical study that found a significant effect on blood pressure health in 89% of trial participants, in 8 weeks or less.

To learn more about what to expect when you start taking PreCardix®, and for best results, please visit us here.

Step 1: Record baseline blood pressure using the PreCardix® app or a blood pressure log. Baseline blood pressure is your blood pressure before starting PreCardix. You can learn how to find your baseline blood pressure here.

Step 2: Take PreCardix as directed.

Step 3: Record blood pressure at the end of each week.

Step 4: Compare week eight blood pressure to baseline blood pressure.

Step 5. Review your results with your health care provider.

Every 2mmHg improvement in blood pressure has a positive effect on outcomes.

To learn more about what to expect when you start taking PreCardix®, and for best results, please visit us here.

If you are just starting to measure your blood pressure at home, it is important to calculate your baseline blood pressure. Measure your blood pressure (before starting PreCardix® twice in the morning and twice in the evening for 7 days in a row. Discard the first day of readings and average the last 6 days. Record in this printable (PDF) or the PreCardix® blood pressure app.  Share this information with your health care provider to discuss your baseline blood pressure readings and how to best support your blood pressure health.

Measure your weekly blood pressure once a week, twice each morning and each evening every day for eight weeks. Record your blood pressure using the PreCardix® blood pressure App or a blood pressure log.

Calculate your average blood pressure using the PreCardix® blood pressure App or a blood pressure log. Compare your baseline blood pressure to your blood pressure after eight weeks. Every 2mmHg improvement in blood pressure has a positive effect on outcomes.

When taking PreCardix® as directed, you may see an improvement in blood pressure within 2-8 weeks. You should take PreCardix® for a minimum of 8 weeks before determining if it works for you. In the clinical trial, 31% of participants experienced a significant effect on their blood pressure compared to baseline after just 2 weeks, while 89% of participants experienced a significant effect in blood pressure compared to baseline after 8 weeks.

Continue to take PreCardix® daily to maintain results.

PreCardix® can be taken to support cardiovascular health. Maintaining healthy blood pressure is especially important if there is a family history of stroke, heart attack or high blood pressure. You can learn more about how PreCardix® can play a crucial role in the management of blood pressure here.

Yes, the peptides in PreCardix® should be considered as part of your daily protein consumption, however they only contain a very small amount of protein. Most official nutrition organizations recommend a modest protein intake of around 0.8 grams of protein per kilogram of body weight. The daily dosage of protein found in PreCardix® is 1.2 grams. If your body weight is 70 kg this means you still need an additional daily protein intake of 54.8 grams.

PreCardix® has been studied in an adult population who are experiencing mild-moderately elevated blood pressure. PreCardix® has not been studied in patients with blood sugar regulation concerns and we have no data to suggest it impacts blood sugar levels.

If you have diabetes and are considering PreCardix® for your blood pressure health, consult with your health care provider before initiating PreCardix®. Share the PreCardix® product monograph with your health care provider who can advise you on drug interactions, contra-indications and other factors related to your health to help determine if PreCardix® is appropriate for you, as well as monitor you closely and effectively.

PreCardix® has not been studied on cholesterol and has not been found to impact cholesterol levels.

PreCardix® tablets contain a unique refined shrimp peptide concentrate (Marealis RSPC). This unique peptide concentrate is derived from the proteins of fresh, cold water Arctic shrimp shells (Pandalus Borealis) through a controlled enzymatic hydrolysis process. Enzymatic hydrolysis breaks down larger protein chains into smaller, peptide chains. These peptide chains are further refined into Marealis RSPC through a proprietary process resulting in a clinically proven bioactive peptide with an ACE inhibiting action.

The amount of active ingredient per recommended daily dosage of 2 tablets is 1,200 mg of shrimp peptide concentrate. In the earlier stages of our research and clinical studies, an important finding was that 1,200 mg of shrimp peptide concentrate is needed daily for it to have a significant effect on blood pressure health. In further clinical studies, 2 tablets of PreCardix® were taken simultaneously daily and 89% of clinical trial participants experienced a significant effect on their blood pressure health within 8 weeks (about 2 months) or less. Therefore, it is important that 2 tablets of PreCardix® are taken together every day.

PreCardix® did not impact serum potassium or kidney function in clinical research. Considering PreCardix® bioactive marine peptides have a natural ACE-inhibiting action, monitoring these parameters along with blood sugars at baseline and throughout treatment may be warranted at your health care provider’s discretion.

You can also learn more about our blood pressure tracking App here.

The PreCardix® box contains 60 tablets. The dosage is 2 tablets per day, therefore one box lasts 30 days.

PreCardix® should be stored at room temperature. It does not need to be refrigerated.

It is important that 2 tablets of PreCardix® are taken together every day.  The amount of active ingredient per recommended daily dosage of 2 tablets is 1,200 mg of shrimp peptide concentrate. In the earlier stages of our research and clinical studies, an important finding was that 1,200 mg of shrimp peptide concentrate is needed daily for it to have a significant effect on blood pressure health. In further clinical studies, 2 tablets of PreCardix® were taken simultaneously daily and 89% of clinical trial participants experienced a significant effect on their blood pressure health within 8 weeks (about 2 months) or less. Therefore, it is important that 2 tablets of PreCardix® are taken together every day.

Skipping a day when taking PreCardix® is not recommended. It advised to adhere to the daily recommended dose to maintain the desired results. The recommended dosage is to take two (2) tablets (1200mg) together once daily, preferably away from food.

Consistency in taking PreCardix® is essential, as discontinuing use may lead to a rise in blood pressure, potentially returning it to pre-treatment levels. Therefore, to achieve and maintain results, it’s encouraged to follow the provided dosing instructions and take PreCardix® consistently each day.