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Heart disease may still be the #1 cause of death globally, but a new wave of natural innovation is gaining ground — and it comes from the sea. Marine peptides, particularly those in clinically studied supplements like PreCardix®, are changing the way we support cardiovascular health, offering science-backed blood pressure support without the side effects of traditional medications.
Whether you’re exploring natural supplements to lower blood pressure or want a more holistic wellness plan, marine peptides deserve your attention. Let’s dive into the science, the benefits, and why these tiny molecules pack a heart-healthy punch.

What Are Marine Peptides?

Marine peptides are short chains of amino acids extracted from marine sources like fish or crustaceans. In the case of PreCardix®, the peptides are derived from the North Atlantic cold-water shrimp (Pandalus borealis) using a unique, eco-friendly enzymatic process.
Unlike full proteins, peptides are smaller and more bioavailable, meaning the body can absorb and use them more efficiently. Specific marine peptides have been shown to have ACE-inhibitory properties — more on that in a moment.

The Science Behind Marine Peptides and Heart Health

The real magic lies in the mechanism of action. Marine peptides, particularly the RSPC bioactive peptides in PreCardix®, work by inhibiting angiotensin-converting enzyme (ACE). This is the same biological target as many pharmaceutical blood pressure drugs, but without the side effects like dry cough, dizziness, or fatigue.

Backed by Decades of Research

PreCardix® is backed by over a decade of rigorous clinical research, including:

  • The MARE study, a preliminary investigation into marine peptide activity
  • The Marealis 13TBHM trial, a peer-reviewed, double-blind, placebo-controlled, multicenter clinical trial involving over 220 participants aged 30 to 75

🔗 View the full clinical trial here

Key Results:

  • 1,200 mg/day of marine peptides significantly improved blood pressure levels
  • 89% of participants saw meaningful changes within 8 weeks or less
  • 43% dropped systolic pressure by over 10mmHg
  • 24% dropped by over 15mmHg
  • No serious adverse effects reported

These findings make marine peptides one of the most compelling natural supplements for high blood pressure on the market today.

Key Cardiovascular Benefits of Marine Peptides

Here’s what makes marine peptides stand out:

  • ACE-Inhibition: Helps relax blood vessels, improving blood flow
  • Supports Vascular Elasticity: Enhances endothelial function
  • Anti-inflammatory Properties: Linked to reduced arterial stiffness
  • Natural Origin: No synthetic ingredients or pharmaceutical interactions
  • Rapid Onset: Effects in as little as 4 to 8 weeks for most users

Marine peptides are uniquely positioned as natural supplements to lower blood pressure while offering whole-body benefits.

How Marine Peptides Compare to Other Heart Health Supplements

Marine peptides offer pharmaceutical-level action with natural safety.

There are many blood pressure support supplements on the market, but few offer clinical backing or targeted mechanisms like marine peptides. Here’s how they compare:

Ingredient

Mechanism

Clinical Evidence

Side Effects

Marine Peptides

ACE-inhibition, sodium balance

High

No serious side effects reported

Garlic Extract

Vasodilation

Low-Moderate Odor, GI upset

Magnesium

Vasodilation

Good

GI discomfort in some

CoQ10

Antioxidant

Moderate

Rare

Who Should Consider Marine Peptides for Heart Health?

  • Adults with mild to moderate high blood pressure
  • Those with a family history of cardiovascular disease
  • People looking for drug-free options with strong clinical evidence
  • Individuals already on medications but looking to support their regimen naturally (always consult your healthcare provider)
Learn more if PreCardix® may be right for you here.

Choosing a High-Quality Marine Peptide Supplement

Not all peptides are created equal. Look for:
  • Clinically tested dosage (like 1,200 mg/day in PreCardix®)
  • Peer-reviewed research
  • Sustainably sourced marine ingredients
  • Transparent labeling and third-party testing
  • Red flags include vague ingredient lists, low dosages, or unsubstantiated claims.

What Users Are Saying

“My blood pressure has been trending upwards with age, increasing stress from work, and overall weight gain. PreCardix seems like a good natural supplement for heart health that is made in Canada. I've been taking it after meals and have not experienced any side effects.” – chunkysoup. Amazon Verified Purchase, June 24 2025. “I've been taking PreCardix for almost a month now and so far my experience with it has been positive: it's easy to take, doesn't make me nauseous or give me indigestion like some other supplements tend to and best of all is that it's not complicated.” – Maxwell, Amazon Verified Purchase, May 26 2025. “This is a great natural way to get your blood pressure down, I love how it doesn't have a taste to it and that they are easy to take, very affordable.” – Alyssa, Amazon Verified Purchase, December 30 2024.. Read more user reviews on Amazon here.

Final Thoughts: A Natural Ally for Your Heart

If you're navigating the overwhelming world of blood pressure supplements, marine peptides offer a rare combination of clinical credibility, natural origin, and real-world results. Products like PreCardix® are leading the charge with peer-reviewed evidence, a proven mechanism of action, and thousands of success stories. When it comes to your heart, it's okay to be choosy. Choose science. Choose nature. Choose smart. Interested in learning more? Explore PreCardix® — the only natural health product in North America with a clinical study on its finished formulation.

Join the PreCardix Canada Community

 

Get in Touch

416-402-0144
1-800-865-9357
support@precardix.ca

The peptides in PreCardix® were studied in a randomized, double-blind, placebo-controlled, multi-centered trial published in the International Journal of Hypertension (Article ID 2345042). While clinical research highlights its potential benefits, PreCardix® is not intended to diagnose, treat, cure, or prevent any disease. Individual outcomes may vary. Always consult a healthcare professional before use.


About PreCardix

Marealis, a Norwegian B Corp, transforms marine by-products into proven, natural ingredients for heart health. PreCardix® offers a science-backed, natural way to support healthy blood pressure.

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